Deep Dives › Gut and Immunity
When someone asks about leaky gut: what the question is really asking, and what to do with it
Take a barrier conviction seriously without endorsing an unvalidated test: where permeability genuinely rises, the differential that actually explains these presentations, why coeliac testing depends on the order of events, and the red flags that end the conversation.
Reviewed by Team SOMA
Last updated August 2026 · English
What you'll be able to do
- âś“Where intestinal permeability genuinely rises, and what it is evidence of when it does
- âś“Why the common permeability tests do not carry the weight put on them
- âś“The differential that actually explains these presentations
- âś“Why coeliac testing depends on the order in which things were done
- âś“The red flags that end this conversation and start a different one
What's inside
Is this for you?
Who it's for
- Anyone with a result in hand who wants the reasoning, not only the conclusion
- People with no medical training - every technical term is explained the moment it appears
- Practitioners who want the thinking behind a number rather than a protocol
What you need
- No prior training. Every technical term is explained in plain words the first time it appears.
- A willingness to read something twice.
About this Deep Dive
Someone arrives convinced their gut is leaking. Dismissing the conviction loses the person; endorsing the test they have brought endorses something that does not hold up. The useful move is neither of those.
What this covers
- Where intestinal permeability genuinely rises, and what it is evidence of when it does
- Why the common permeability tests do not carry the weight put on them
- The differential that actually explains these presentations
- Why coeliac testing depends on the order in which things were done
- The red flags that end this conversation and start a different one
How it is built
Five parts, taken in order: a short orientation, the reading itself, one worked case, a check to see whether it landed, and a page on what changes once you have it. About forty minutes, and it is written to be read twice. There is no certificate here — that is what the Certified Programmes are for.
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