Journal

Long form writing on physiology and clinical reasoning

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cell membranes, macroNewest · Cellular Health and MitochondriaTesting mitochondrial function without a biopsyThe reference test for mitochondrial function needs a piece of muscle. Everything short of that is indirect, and read together the indirect signals answer most of the question.4 min read · 20 September 2026
Dark ink wisp rising and clearing above bright waterToxins and XenobioticsWhat are xenobiotics, and why some of them lingerThe body treats a painkiller and a paint solvent with the same chemistry. What changes the outcome is where a…4 min read · 20 September 2026a luminous strand dissolving into particles, macroLongevityGrip strength: what a one-minute test predictsA minute with a hand dynamometer tells you more about the next decade than most of the blood panel taken…4 min read · 20 September 2026a living ecosystem of soft forms and spheres, macroGut and ImmunityZonulin and leaky gut: what the test can showThe gut barrier is real, measurable and well studied. The popular blood marker for it is the weakest part of…4 min read · 20 September 2026oxygen bubbles in fluid, macroOzone and Regenerative TherapiesOzone therapy dosing: concentration, volume, routeTwo clinics can both say they gave a course of ozone and mean doses that differ threefold. The arithmetic behind…4 min read · 20 September 2026crystals dissolving into warm fluid, macroMetabolic Health and DiabetesWhat a normal fasting insulin actually isA fasting insulin inside the laboratory range can still describe a system working hard to look normal, and it moves…4 min read · 20 September 2026a signal droplet meeting a membrane, macroHormonesHow to read a four-point cortisol curveA cortisol result inside the reference range can still be the wrong shape, and the shape is what changes what…5 min read · 20 September 2026Fine fragments drifting in still pale water, an abstract image of slow clearanceToxins and XenobioticsDo detoxes work? What actually helps clearanceA cleanse promises to switch on a process that never switches off. What actually limits elimination is more ordinary, and…6 min read · 26 August 2026Diffuse amber trails converging in deep water, an abstract image of mixed exposuresToxins and XenobioticsWhere “the dose makes the poison” breaks downThe dose principle is one of the most useful ideas in medicine, and it is incomplete in three specific ways:…5 min read · 26 August 2026Golden threads entering and leaving a dark field, an abstract image of rate rather than presenceToxins and XenobioticsHow chemical exposure actually adds upAccumulation is arithmetic: what comes in, minus what goes out, over time. Drop any one of those three terms and…6 min read · 26 August 2026
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