Journal

Long form writing on physiology and clinical reasoning

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Interwoven indigo tendrils descending through clear waterLongevityWhy age-related diseases arrive togetherBlood pressure that crept up in the fifties, a fasting glucose drifting a point a year, sleep that no longer…6 min read · 26 August 2026Smooth undulating ridges in a reflective liquid surfaceHormonesA regular cycle is not proof of ovulationTwenty-eight days, every month, for as long as she can remember. The regularity is real, and on its own it…6 min read · 26 August 2026Rose and violet interference patterns thinning across a surfaceHormonesA low testosterone result: what to examine firstTwo 46-year-olds get the same number back, below the reference range. Almost nothing else about it is the same. A…6 min read · 26 August 2026A cyclical band of iridescence curving across dark waterHormonesCortisol, the waking response, and adrenal fatigueAwake at seven, upright by half past, functioning at about eleven. In large groups describing exactly that, the daily cortisol…6 min read · 26 August 2026Pale interference colours spreading over still dark waterHormonesNormal thyroid labs and still cold, tired and slowTSH is not a thyroid measurement. It is a pituitary one, the size of the request being sent, and it…6 min read · 26 August 2026A dense mat of overlapping fine filaments seen from aboveGut and ImmunityGut and brain: five channels, and the serotonin claimMost of the body's serotonin is made in the gut, not the brain. It is true, and it is one…6 min read · 26 August 2026Soft coral-like structures under diffused lightGut and ImmunityFood reactions: what the tests mean and what they do notIt starts with two foods. Eighteen months on, the list runs to nineteen items and the reactions have not stopped.…6 min read · 26 August 2026Closely packed organic forms with narrow gaps between themGut and ImmunityLeaky gut: what is real and what is being soldSearch the term and you land in one of two internets: a failing barrier that explains fatigue, eczema and low…6 min read · 26 August 2026Fine branching structures in pale blush and sageGut and ImmunityWhy fibre works even though you cannot digest itHumans make no enzyme that can open the bonds in most plant fibre. By the strict logic of nutrition that…6 min read · 26 August 2026Points of warm light scattered at varying depths in darknessCellular Health and MitochondriaMitochondria and ageing: why quality beats quantityTwo people of the same age give a small muscle sample and the mitochondrial counts come back similar. One takes…6 min read · 26 August 2026
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